Research Technician - School of Medicine-16001802
The department of integrative physiology and pathobiology is a community of scientists focused on the genesis and treatment of chronic and genetic disease. While individual faculty members have studied a variety of clinical problems, including arthritis, autoimmune disorders, birth defects, cancer, cardiovascular disease, infectious pathology, metabolic and neurological disease, obesity, reproductive disorders, and wound healing, there is a core thread of effort to understand the inflammatory response and the regeneration and repair mechanisms that restore normal functioning to damaged tissue. The name integrative physiology and pathobiology reflects the fact that faculty members in the department are using a wide breadth of approaches to look at the whole organism and its component molecules, cells and tissues. The faculty members address fundamental questions in normal physiology and the mechanism of human disease.
The research in our laboratory is focused on understanding the molecular mechanisms controlling the identity and functional states of CD4 helper T lymphocytes and how their dysregulation leads to the loss of immune homeostasis in various disease settings. Major interests include: the roles of cis-regulatory DNA elements in controlling cellular identities of CD4 T cells; the molecular mechanisms by which CD4 T cells functionally adapt to tissue and immune microenvironments. This is a position in a new research group, and we seek a motivated individual who is enthusiastic to learn and work with the group on questions related to this research focus. Under supervision of the Principal Investigator, the Research Technician will conduct a variety of experiments following established procedures/protocols, which may include bacterial and mammalian cell culture, retroviral vector production, flow cytometry, PCR and electrophoresis, DNA and RNA extraction and characterization, mouse colony management, mouse models of autoimmune diseases, and other laboratory techniques. In these capacities, the Technician will also record test results and analyze data using basic statistics and various software. In addition, the Technician will assist in monitoring animal colonies, help set up the new laboratory, and then monitor the functioning of laboratory equipment, and organize and maintain logbooks and supplies.
• Bachelor's degree in Biology, Biochemistry, Microbiology/Immunology, or related fields, with up to one year of laboratory experience.
• Proficient in using Microsoft Office products.
• Must be able to fluently communicate, read, and write in the English language.
• Self-motivation, consistent attention to detail, and excellent organizational, communication, and time management skills are critical.
• Previous experience using molecular biology, cell biology, and immunology techniques is highly preferred.
• Previous experience working with mice as a research model is preferred but not required, although willingness to be trained to work with mice is necessary.
Special Work Schedule Requirements:
May work with and be exposed to hazardous chemicals and materials, human/animal tissue and fluids, radiation. Occasional need to work overtime, holidays, or weekends.
Tufts University is an AA/EO employer and actively seeks candidates from diverse backgrounds. Please see the Tufts University non-discrimination statement.
Primary Location: United States-Massachusetts-Boston
Organization: Int Physiol & Pathobio/Medical
Employee Status: Regular
Job Posting: Nov 30, 2016, 10:59:59 AM